行业的洞察力
一起筛选:Academia-industrial合作的好处
行业的洞察力
一起筛选:Academia-industrial合作的好处
Academic Screening Workshop a whole session is dedicated to this subject. Professor Richard Neubig, from the University of Michigan will be talking about how he is reversing the traditional screening paradigm to uncover compounds that are effective against human scleroderma dermal fibroblasts. Whereas standard screening usually involves the identification of a molecular target for the disease first and then screening a number of compounds for their activity against that marker, Dr Neubig is identifying compounds that have activity against the cells themselves first without knowing what the molecular marker is.
Fostering Collaboration
Most importantly, we believe that focusing on collaboration and knowledge sharing within the screening industry is one of the best ways to overcome the current challenges within the field. The time has come for industry and academia to work together to innovate and catalyse translational research. That's why the format of the Academic Screening Workshop includes two full afternoons of panel discussions, enabling attendees to pose questions and start discussions with some of the industry's leading lights from academia, industry and equipment vendors.
Most importantly, we believe that focusing on collaboration and knowledge sharing within the screening industry is one of the best ways to overcome the current challenges within the field. The time has come for industry and academia to work together to innovate and catalyse translational research. That's why the format of the Academic Screening Workshop includes two full afternoons of panel discussions, enabling attendees to pose questions and start discussions with some of the industry's leading lights from academia, industry and equipment vendors.
Developing New Assays
Particular focus should be given to the development of strategic partnerships and collaborations that could lead to advancements and breakthroughs in new assay development. This area is of vital importance if we are to make the path towards new clinical entities easier and more cost effective. For example, the increasing use and importance of RNAi screening, a technique that enables the dissection and elucidation of complex biological processes by silencing gene expression, has the potential to uncover disease targets and aid therapeutic development. However, the technique still requires significant assay development, especially when it comes to pooled RNAi screening approaches in complex cell model systems. This is proving frustrating for a number of laboratories and screening centres, because despite its obvious potential, RNAi screening has yet to deliver the meaningful results that its potential merits.
Find out more at the Academic Screening Workshop 2013
Organised in collaboration with Dr Hakim Djaballah of the Memorial Sloan Kettering Cancer Center, the Academic Screening Workshop is into its 3rd year of providing a forum for delegates to discuss and share their experiences on all things drug discovery.
If you would like to be kept updated on this year's event, then why not signup to the eNewsletter.
Alternatively, you can register right now by visiting the event sign up page.
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Particular focus should be given to the development of strategic partnerships and collaborations that could lead to advancements and breakthroughs in new assay development. This area is of vital importance if we are to make the path towards new clinical entities easier and more cost effective. For example, the increasing use and importance of RNAi screening, a technique that enables the dissection and elucidation of complex biological processes by silencing gene expression, has the potential to uncover disease targets and aid therapeutic development. However, the technique still requires significant assay development, especially when it comes to pooled RNAi screening approaches in complex cell model systems. This is proving frustrating for a number of laboratories and screening centres, because despite its obvious potential, RNAi screening has yet to deliver the meaningful results that its potential merits.
Find out more at the Academic Screening Workshop 2013
Organised in collaboration with Dr Hakim Djaballah of the Memorial Sloan Kettering Cancer Center, the Academic Screening Workshop is into its 3rd year of providing a forum for delegates to discuss and share their experiences on all things drug discovery.
If you would like to be kept updated on this year's event, then why not signup to the eNewsletter.
Alternatively, you can register right now by visiting the event sign up page.
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academia-industrial合作的好处
鉴于目前的金融环境,许多学术筛查中心接受政府资助的减少和面临越来越大的压力,以降低成本。在这个博客中,我们看看如何培养协作和知识共享的学术界和产业界之间可能增长提供一些解决这些问题。在这一过程中,我们希望提供一些隧道尽头的光的筛查实验室寻找新的资金来源和研究的想法。
鉴于目前的金融环境,许多学术筛查中心接受政府资助的减少和面临越来越大的压力,以降低成本。在这个博客中,我们看看如何培养协作和知识共享的学术界和产业界之间可能增长提供一些解决这些问题。在这一过程中,我们希望提供一些隧道尽头的光的筛查实验室寻找新的资金来源和研究的想法。
针对被忽视的疾病
从人的本性来讲,学术筛查实验室可以相对自由地调查他们选择的任何疾病,从金融动机没有显著影响。这样,他们有灵活性和适应性筛选候选药物,大型制药公司将考虑在经济上不可行,比如针对条件影响小患者群体或疾病相关的发展中国家。越来越多的,这些所谓的“孤儿病”正在有针对性的学术实验室与大型制药公司合作。这种协作模型是由许多项目被FDA煽动,“孤儿药名称”等项目,为机构和企业提供获得额外的资金和激励目标这些条件。这一点,再加上一些最近的技术进步和创新思维,使得研究人员调查取得进展许多条件,以前认为是无药可治的。
从人的本性来讲,学术筛查实验室可以相对自由地调查他们选择的任何疾病,从金融动机没有显著影响。这样,他们有灵活性和适应性筛选候选药物,大型制药公司将考虑在经济上不可行,比如针对条件影响小患者群体或疾病相关的发展中国家。越来越多的,这些所谓的“孤儿病”正在有针对性的学术实验室与大型制药公司合作。这种协作模型是由许多项目被FDA煽动,“孤儿药名称”等项目,为机构和企业提供获得额外的资金和激励目标这些条件。这一点,再加上一些最近的技术进步和创新思维,使得研究人员调查取得进展许多条件,以前认为是无药可治的。
在选择生物即将到来的学术审查研讨会整个会议致力于这一主题。从密歇根大学教授理查德•Neubig将谈论他如何扭转传统的筛查模式发现对人类有效硬皮病皮肤成纤维细胞的化合物。而标准筛选通常涉及疾病的分子目标的识别,然后筛选大量的化合物对标记,他们的活动Neubig博士确定化合物对细胞活动自己首先不知道分子标记。
培养协作
最重要的是,我们相信筛查业内关注协作和知识共享是一个最好的方法来克服当前的困难。的时候到了工业和学术界共同创新和催化转化研究。这就是为什么的格式学术审查研讨会包括两个下午的小组讨论,使与会者提问,开始讨论一些行业领先的灯光从学术界、工业和设备供应商。
最重要的是,我们相信筛查业内关注协作和知识共享是一个最好的方法来克服当前的困难。的时候到了工业和学术界共同创新和催化转化研究。这就是为什么的格式学术审查研讨会包括两个下午的小组讨论,使与会者提问,开始讨论一些行业领先的灯光从学术界、工业和设备供应商。
开发新的化验
应特别关注发展的战略伙伴关系和协作,可能导致新的分析方法发展的进步和突破。这个地区是至关重要的,如果我们要让朝着新的临床实体变得更容易、更划算。例如,增加使用和RNAi筛查的重要性,一个技术,使复杂的生物过程的解剖和说明沉默基因表达,有可能发现疾病治疗发展目标和援助。然而,这项技术还需要大量的试验开发,特别是汇集RNAi筛选方法在复杂的细胞模型系统。这是证明令人沮丧的实验室和检测中心,因为尽管它明显的潜力,RNAi筛查尚未提供有意义的结果,其潜在的优点。
找到更多的学术筛选车间2013
组织合作的哈基姆Djaballah博士纪念斯隆凯特林癌症中心,学术筛选车间是进入第三年为代表提供一个论坛,讨论并分享他们的经验在药物发现。比利时罗马尼亚比分直播
如果你想保持更新在今年的事件,那么为什么不注册到eNewsletter。
或者,您可以注册现在通过访问事件注册页面。
应特别关注发展的战略伙伴关系和协作,可能导致新的分析方法发展的进步和突破。这个地区是至关重要的,如果我们要让朝着新的临床实体变得更容易、更划算。例如,增加使用和RNAi筛查的重要性,一个技术,使复杂的生物过程的解剖和说明沉默基因表达,有可能发现疾病治疗发展目标和援助。然而,这项技术还需要大量的试验开发,特别是汇集RNAi筛选方法在复杂的细胞模型系统。这是证明令人沮丧的实验室和检测中心,因为尽管它明显的潜力,RNAi筛查尚未提供有意义的结果,其潜在的优点。
找到更多的学术筛选车间2013
组织合作的哈基姆Djaballah博士纪念斯隆凯特林癌症中心,学术筛选车间是进入第三年为代表提供一个论坛,讨论并分享他们的经验在药物发现。比利时罗马尼亚比分直播
如果你想保持更新在今年的事件,那么为什么不注册到eNewsletter。
或者,您可以注册现在通过访问事件注册页面。
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